Main
Michael J. Sieler Jr.
Summary
• Microbiome scientist with 5+ years of experience developing and applying high-throughput molecular, computational, and statistical research methods to analyze 1000’s of zebrafish gut microbiome samples
• Research how multiple environmental factors interact with the gut microbiome to influence host health
• Robust data analytic skills in multivariate statistics and machine learning propel research experiments forward and gain data-driven insights
• Demonstrated abilities to collaborate and take leadership in cross-laboratory experiments and extra-curricular projects
• Experienced in written, oral and visual communication across scientific and public audiences
Education
Ph.D. Microbiology, minor in Biological Data Sciences
Oregon State University
Corvallis, Oregon
2020 - estimated 2025
B.Sc. Bioresource Research, options in Bioinformatics and Genomics
Oregon State University
Corvallis, Oregon
2017 - 2020
Professional Experience
Owner
MJSieler Consulting
Corvallis, Oregon
May 2022 - Present
• Designed, developed, and deployed educational video game software for clients to fulfill grant requirements for communicating scientific research
Projects: Virtual Fish
Tools: C#, Unity, Python, SQL
Graduate Research Student
Sharpton Lab (Oregon State University)
Corvallis, Oregon
Sep. 2020 - Present
• Investigate how environmental factors (diet, pollutants, pathogens, etc.) interact with the gut microbiome to influence host health using the zebrafish model organism • Developed multivariate statistical and bioinformatic pipelines for analyzing 100’s of microbiome samples using R, Python and Command Line Tools • Led cross-laboratory scientific experiments from planning, design, implementation and analysis stages using 100’s of zebrafish across an array of treatments • Co-authored 3 scientific articles • Co-taught 70+ student microbiology labs
Projects: Impacts of diet & infection, temperature & infection, and chronic antibiotic exposure on gut microbiome. Microbial Bioinformatics Hub
Tools: R, Python, Microbial bioinformatics, multivariant statistics, machine learning, Unix/Linux, zebrafish husbandry
Undergraduate Research Student
Sharpton & Mahmud Labs (Oregon State University)
Corvallis, Oregon
Nov. 2017 - Sep. 2020
• Developed and implemented novel, high-throughput gnotobiotic microbiome methods to simultaneously process +1000 zebrafish embryos for microbiome and toxicological research • Identified dozens of putative antibiotic compound from streptomyces bacteria
Projects: Benzo[a]pyrene effect on zebrafish gut microbiome
Tools: R, Microbial bioinformatics, Zebrafish husbandry, molecular wet lab techniques