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Michael J. Sieler Jr. 

Summary

• Microbiome scientist with 5+ years of experience developing and applying high-throughput molecular, computational, and statistical research methods to analyze 1000’s of zebrafish gut microbiome samples

• Research how multiple environmental factors interact with the gut microbiome to influence host health

• Robust data analytic skills in multivariate statistics and machine learning propel research experiments forward and gain data-driven insights

• Demonstrated abilities to collaborate and take leadership in cross-laboratory experiments and extra-curricular projects

• Experienced in written, oral and visual communication across scientific and public audiences

Education

Ph.D. Microbiology, minor in Biological Data Sciences

Oregon State University

Corvallis, Oregon

2020 - estimated 2025

B.Sc. Bioresource Research, options in Bioinformatics and Genomics

Oregon State University

Corvallis, Oregon

2017 - 2020

Professional Experience

Owner

MJSieler Consulting

Corvallis, Oregon

May 2022 - Present

• Designed, developed, and deployed educational video game software for clients to fulfill grant requirements for communicating scientific research

Projects: Virtual Fish

Tools: C#, Unity, Python, SQL

Graduate Research Student

Sharpton Lab (Oregon State University)

Corvallis, Oregon

Sep. 2020 - Present

• Investigate how environmental factors (diet, pollutants, pathogens, etc.) interact with the gut microbiome to influence host health using the zebrafish model organism • Developed multivariate statistical and bioinformatic pipelines for analyzing 100’s of microbiome samples using R, Python and Command Line Tools • Led cross-laboratory scientific experiments from planning, design, implementation and analysis stages using 100’s of zebrafish across an array of treatments • Co-authored 3 scientific articles • Co-taught 70+ student microbiology labs

Projects: Impacts of diet & infection, temperature & infection, and chronic antibiotic exposure on gut microbiome. Microbial Bioinformatics Hub

Tools: R, Python, Microbial bioinformatics, multivariant statistics, machine learning, Unix/Linux, zebrafish husbandry

Undergraduate Research Student

Sharpton & Mahmud Labs (Oregon State University)

Corvallis, Oregon

Nov. 2017 - Sep. 2020

• Developed and implemented novel, high-throughput gnotobiotic microbiome methods to simultaneously process +1000 zebrafish embryos for microbiome and toxicological research • Identified dozens of putative antibiotic compound from streptomyces bacteria

Projects: Benzo[a]pyrene effect on zebrafish gut microbiome

Tools: R, Microbial bioinformatics, Zebrafish husbandry, molecular wet lab techniques